Facilitation of chromatin dynamics by SARs
Metaphase chromosome condensation is a dynamic process that must utilize cis elements to form and maintain the final structure. Likewise, cis elements must regulate the accessibility of chromatin domains to protein machines involved in processes such as transcription. Scaffold associated regions appear to play important roles in both of these dynamic processes.
Publication Source (Journal or Book title)
Current Opinion in Genetics and Development
Hart, C., & Laemmli, U. (1998). Facilitation of chromatin dynamics by SARs. Current Opinion in Genetics and Development, 8 (5), 519-525. https://doi.org/10.1016/S0959-437X(98)80005-1