Title
Synthesis and characterization of PLGA nanoparticles
Document Type
Article
Publication Date
1-1-2006
Abstract
Poly(lactide-co-glycolide) (PLGA) nanoparticles of different physical characteristics (size, size distribution, morphology, zeta potential) can be synthesized by controlling the parameters specific to the synthesis method employed. The aim of this review is to clearly, quantitatively and comprehensively describe the top-down synthesis techniques available for PLGA nanoparticle formation, as well as the techniques commonly used for nanoparticle characterization. Many examples are discussed in detail to provide the reader with an extensive knowledge base on the important parameters specific to the synthesis method described and ways in which these parameters can be manipulated to control the nanoparticle physical characteristics.
Publication Source (Journal or Book title)
Journal of biomaterials science. Polymer edition
First Page
247
Last Page
89
Recommended Citation
Astete, C. E., & Sabliov, C. M. (2006). Synthesis and characterization of PLGA nanoparticles. Journal of biomaterials science. Polymer edition, 17 (3), 247-89. https://doi.org/10.1163/156856206775997322