Spatio-temporal thermal kinetics of in situ MWCNT heating in biological tissues under NIR laser irradiation
Carbon nanotubes have many potential applications in life sciences and engineering as they have very high absorbance in the near-infrared (NIR) spectrum, while biological tissues do not. The purpose of this study was to determine the effect of 1064 nm NIR laser power levels on the spatial temperature distribution and the temperature kinetics in mammalian tissue at both macroscopic and microscopic scales. The model tissue was the 'flat' of a chicken wing (the section containing the radius and ulna), which was injected under the skin in the subcutaneous layer of tissue. Specimens were exposed to laser radiation and an infrared thermography system was used to measure and record the temperature distributions in the specimens at both the macroscopic and microscopic scales. Experimental results concluded that power levels of 1536 mW easily achieved hyperthermic temperatures with localized values as high as 172.7 °C.
Publication Source (Journal or Book title)
Picou, L., McMann, C., Elzer, P. H., Enright, F. M., Biris, A. S., & Boldor, D. (2010). Spatio-temporal thermal kinetics of in situ MWCNT heating in biological tissues under NIR laser irradiation. Nanotechnology, 21 (43), 435101. https://doi.org/10.1088/0957-4484/21/43/435101