Title
Mesenchymal Stromal Cells: Past, Present, and Future
Document Type
Article
Publication Date
2-1-2011
Abstract
Adult mesenchymal stromal cells are plastic-adherent cells that are self-renewing and have the capacity to differentiate into various tissue specific lineages. Stromal cells were initially discovered over 100 years ago and substantial insight into stromal cell identification, isolation, characterization, and differentiation has been made, including efforts to elucidate the factors involved in stromal cell differentiation. Stromal cells have immune privilege and thus are attractive candidates for tissue engineering and regenerative medicine applications. Positive results from a number of recent investigations support the use of adult mesenchymal stromal cells for clinical application. This review article provides a brief overview of past, present, and future stromal cell technology.
Publication Source (Journal or Book title)
Veterinary surgery : VS
First Page
129
Last Page
39
Recommended Citation
Spencer, N. D., Gimble, J. M., & Lopez, M. J. (2011). Mesenchymal Stromal Cells: Past, Present, and Future. Veterinary surgery : VS, 40 (2), 129-39. https://doi.org/10.1111/j.1532-950X.2010.00776.x