Title
Effect of the ionophore monensin on herpes simplex virus Type 1-induced cell fusion, glycoprotein synthesis, and virion infectivity
Document Type
Article
Publication Date
1-1-1983
Abstract
The ionophore monensin inhibited the formation of mature, fully glycosylated glycoproteins gB, gC, and gD during herpes simplex virus type 1 infection of human embryonic lung cells. Underglycosylated forms, including the apparent high-mannose precursor forms of the major glycoproteins, appeared. Monensin inhibited virus-induced cell fusion. Infectious virions produced in the presence of monensin appeared to contain predominantly underglycosylated glycoproteins. © 1983 S. Karger AG, Basel.
Publication Source (Journal or Book title)
Intervirology
First Page
56
Last Page
60
Recommended Citation
Kousoulas, K., Bzik, D., & Person, S. (1983). Effect of the ionophore monensin on herpes simplex virus Type 1-induced cell fusion, glycoprotein synthesis, and virion infectivity. Intervirology, 20 (1), 56-60. https://doi.org/10.1159/000149375