Mitochondrial dysfunction and ovarian aging
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Mitochondria are double-membrane-bound organelles that are responsible for the generation of most of the cell's energy. Mitochondrial dysfunction has been implicated in cellular senescence in general and ovarian aging in particular. Recent studies exploited this association by studying mitochondrial DNA (mtDNA) copy number as a potential biomarker of embryo viability and the use of mitochondrial nutrients and autologous mitochondrial transfer as a potential treatment for poor ovarian function and response.
Publication Source (Journal or Book title)
American Journal of Reproductive Immunology
Wang, T., Zhang, M., Jiang, Z., & Seli, E. (2017). Mitochondrial dysfunction and ovarian aging. American Journal of Reproductive Immunology, 77 (5) https://doi.org/10.1111/aji.12651