Title

Ciprofloxacin treatment eliminates mycoplasma in contaminated channel catfish ovary cells

Document Type

Article

Publication Date

1-1-1994

Abstract

A temperature-sensitive mycoplasma that was present in the channel catfish ovary (CCO) cell line and in a thymidine kinase-negative mutant of this cell line (CCOBr) was effectively eliminated from the cultures by adding ciprofloxacin, a 4-fluoroquinolone, to the culture medium. Both cell lines have remained mycoplasma free after 3 years of continuous culture. A commercially available genetic probe to mycoplasma ribosomal RNA was used to monitor mycoplasma contamination and evaluate the effectiveness of the treatment. © by the American Fisheries Society 1994.

Publication Source (Journal or Book title)

Journal of Aquatic Animal Health

First Page

82

Last Page

84

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