Title

ACUTE AND CHRONIC EFFECTS OF COCAINE ON EXTINCTION‐INDUCED AGGRESSION

Document Type

Article

Publication Date

1-1-1978

Abstract

Pigeons worked individually in a chamber containing a response key and a mirror. Pecking on the key was controlled by a multiple schedule in which a brief period of continuous food reinforcement alternated with a 5‐minute period of extinction. Under baseline conditions, aggressive behavior (responding on the mirror) occurred at the onset of each extinction period. In Experiment I (acute drug administration), the aggressive behavior was decreased by doses of cocaine that had little or no effect on key pecking. Such food‐reinforced responding was disrupted, however, by higher doses of cocaine. An attempt to mimic the disruptive drug effects by a prefeeding manipulation was unsuccessful. In Experiment II (chronic drug administration), some tolerance developed to the disruptive effects of cocaine on the food‐reinforced responding, except at the highest dose tested. There was no clear‐cut indication of tolerance to the initial effect of cocaine on the aggressive behavior at any dose. 1978 Society for the Experimental Analysis of Behavior

Publication Source (Journal or Book title)

Journal of the Experimental Analysis of Behavior

First Page

309

Last Page

318

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