Title

EFFECTS OF METHAMPHETAMINE AND SCOPOLAMINE ON VARIABILITY OF RESPONSE LOCATION

Document Type

Article

Publication Date

1-1-1979

Abstract

Methamphetamine and scopolamine were studied in monkeys responding under a multiple fixed‐ratio fixed‐interval schedule of reinforcement. A response on any one of six levers could satisfy the schedule requirements. Variability of response location was evaluated in terms of switches, where a switch was defined as a response on one lever followed by a response on a different lever. Under baseline conditions the fixed‐ratio schedule generated a high rate of responding and a low level of variability, while the fixed‐interval schedule generated a low rate of responding and a high level of variability. Both methamphetamine (0.1 to 0.5 mg/kg) and scopolamine (2.4 to 240 μg/kg) decreased overall response rate and increased variability of response location in each component of the multiple schedule with increasing doses of drug. At lower doses both drugs were found to decrease rate without affecting response variability. 1979 Society for the Experimental Analysis of Behavior

Publication Source (Journal or Book title)

Journal of the Experimental Analysis of Behavior

First Page

255

Last Page

263

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