Master of Science (MS)
Electrical and Computer Engineering
In this research, a rapid prototype of multi-fluidic speed-modulating (MFSM) micropump which enables modulation of hydrodynamic focusing in micro-fluidic flow has been designed, fabricated, and characterized. The size of the entire module is 33 mm x 25 mm x 8 mm and comprises of three MFSM micropumps to achieve hydrodynamic focusing. These pumps are simultaneously operated by the same actuation source. Each micropump consists of Tesla-type valves in the bottom layer and PDMS/Ni-particle composite (PNPC) diaphragm in the middle layer. The deflection of the diaphragm is obtained by the external pneumatic force, and the permanent magnet controls the displacement resulting from interaction between the magnetic field and the PNPC diaphragm. Analyses of the magnetic modulation force, the flow rate of the MFSM micropump, and the hydrodynamic focused channel modulation are presented. The individual micropump can pump DI water at flow rate of 107 ìl/min, and the combination of the three micropumps is able to make the flow rate of 321 ìl/min within a hydrodynamic focusing channel. This research successfully examines the possibility of modulation of a neighboring channel flow rate through interaction with a magnetic force field to achieve hydrodynamic focusing of flow in the central channel. With appropriate magnetic interaction with diaphragm, the central channel flow width can also be varied. This technique can be utilized for possible application in drug delivery system (DDS), lab-on-a-chip (LOC) or micro total analysis system (ìTAS), and in a point of care testing (POCT) system.
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Kim, Jeonghwan, "Hydrodynamic focusing micropump module with PDMS/nickel-particle composite diaphragms for microfluidic systems" (2011). LSU Master's Theses. 2641.
Ajmera, Pratul K.